Downregulation of lengthy noncoding RNA SNHG6 rescued propofol-induced

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1bp1

A novel platform to speed up antimicrobial susceptibility testing in Neisseria gonorrhoeae utilizing RNA signatures

The rise of antimicrobial-resistant pathogens could be attributed to the shortage of a speedy pathogen identification (ID) or antimicrobial susceptibility testing (AST), leading to delayed therapeutic choices on the point-of-care. Gonorrhea is often empirically handled with no AST outcomes obtainable earlier than therapy, thus contributing to the speedy rise in drug resistance.

Herein we current a speedy AST platform utilizing RNA signatures for Neisseria gonorrhoeae (NG). RNA-seq adopted by bioinformatic instruments had been utilized to discover potential markers within the transcriptome profile of NG upon minutes of azithromycin publicity. Validation of candidate markers utilizing qRT-PCR confirmed that two markers (arsR (NGO1562) and rpsO) can ship correct AST outcomes throughout 14 examined isolates.

Additional validation of our susceptibility threshold compared to MIC throughout 64 extra isolates confirmed the reliability of our platform. Our RNA markers mixed with rising molecular point-of-care programs has the potential to significantly speed up each ID and AST to tell therapy.

1bp1
1bp1

Canine Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

DLR-BDNF-c-48T 48T
EUR 568.8
Description: A sandwich quantitative ELISA assay kit for detection of Canine Brain Derived Neurotrophic Factor (BDNF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Canine Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

DLR-BDNF-c-96T 96T
EUR 736.8
Description: A sandwich quantitative ELISA assay kit for detection of Canine Brain Derived Neurotrophic Factor (BDNF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Chicken Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

DLR-BDNF-Ch-48T 48T
EUR 544.8
Description: A sandwich quantitative ELISA assay kit for detection of Chicken Brain Derived Neurotrophic Factor (BDNF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Chicken Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

DLR-BDNF-Ch-96T 96T
EUR 704.4
Description: A sandwich quantitative ELISA assay kit for detection of Chicken Brain Derived Neurotrophic Factor (BDNF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

DLR-BDNF-Mu-48T 48T
EUR 522
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Brain Derived Neurotrophic Factor (BDNF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

DLR-BDNF-Mu-96T 96T
EUR 673.2
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Brain Derived Neurotrophic Factor (BDNF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

DLR-BDNF-p-48T 48T
EUR 591.6
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Brain Derived Neurotrophic Factor (BDNF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

DLR-BDNF-p-96T 96T
EUR 769.2
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Brain Derived Neurotrophic Factor (BDNF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

DLR-BDNF-Ra-48T 48T
EUR 495.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat Brain Derived Neurotrophic Factor (BDNF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

DLR-BDNF-Ra-96T 96T
EUR 637.2
Description: A sandwich quantitative ELISA assay kit for detection of Rat Brain Derived Neurotrophic Factor (BDNF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

DLR-BDNF-Rb-48T 48T
EUR 544.8
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Brain Derived Neurotrophic Factor (BDNF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

DLR-BDNF-Rb-96T 96T
EUR 704.4
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Brain Derived Neurotrophic Factor (BDNF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Canine Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RDR-BDNF-c-48Tests 48 Tests
EUR 591.6

Canine Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RDR-BDNF-c-96Tests 96 Tests
EUR 819.6

Chicken Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RDR-BDNF-Ch-48Tests 48 Tests
EUR 564

Chicken Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RDR-BDNF-Ch-96Tests 96 Tests
EUR 781.2

Mouse Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RDR-BDNF-Mu-48Tests 48 Tests
EUR 536.4

Mouse Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RDR-BDNF-Mu-96Tests 96 Tests
EUR 741.6

Porcine Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RDR-BDNF-p-48Tests 48 Tests
EUR 619.2

Porcine Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RDR-BDNF-p-96Tests 96 Tests
EUR 859.2

Rat Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RDR-BDNF-Ra-48Tests 48 Tests
EUR 506.4

Rat Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RDR-BDNF-Ra-96Tests 96 Tests
EUR 697.2

Rabbit Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RDR-BDNF-Rb-48Tests 48 Tests
EUR 564

Rabbit Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RDR-BDNF-Rb-96Tests 96 Tests
EUR 781.2

Canine Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RD-BDNF-c-48Tests 48 Tests
EUR 566.4

Canine Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RD-BDNF-c-96Tests 96 Tests
EUR 783.6

Chicken Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RD-BDNF-Ch-48Tests 48 Tests
EUR 540

Chicken Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RD-BDNF-Ch-96Tests 96 Tests
EUR 746.4

Mouse Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RD-BDNF-Mu-48Tests 48 Tests
EUR 514.8

Mouse Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RD-BDNF-Mu-96Tests 96 Tests
EUR 709.2

Porcine Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RD-BDNF-p-48Tests 48 Tests
EUR 592.8

Porcine Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RD-BDNF-p-96Tests 96 Tests
EUR 820.8

Rat Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RD-BDNF-Ra-48Tests 48 Tests
EUR 484.8

Rat Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RD-BDNF-Ra-96Tests 96 Tests
EUR 667.2

Rabbit Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RD-BDNF-Rb-48Tests 48 Tests
EUR 540

Rabbit Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RD-BDNF-Rb-96Tests 96 Tests
EUR 746.4

anti- BDNF antibody

FNab00859 100µg
EUR 606.3
Description: Antibody raised against BDNF

Anti-BDNF Antibody

PA1014 100ug/vial
EUR 352.8

anti- BDNF antibody

FNab10014 100µg
EUR 658.5
Description: Antibody raised against BDNF

Anti-BDNF Antibody

PB9075 100ug/vial
EUR 400.8

Anti-BDNF antibody

PAab00859 100 ug
EUR 426

Anti-BDNF antibody

STJ112899 100 µl
EUR 332.4
Description: This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.

Anti-BDNF antibody

STJ11100099 100 µl
EUR 471.6
Description: This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.

Anti-BDNF antibody

STJ13100049 100 µl
EUR 512.4

Anti-BDNF antibody

STJ13100050 500 µg
EUR 512.4

Anti-BDNF antibody

STJ13100052 100 µl
EUR 512.4

Anti-BDNF antibody

STJ13100053 500 µg
EUR 512.4

Anti-BDNF antibody

STJ13100054 50 µg
EUR 512.4

Anti-BDNF antibody

STJ13100055 100 µg
EUR 512.4

Anti-BDNF Antibody

STJ60048 100 µg
EUR 508.8

Anti-BDNF Antibody

STJ60049 100 µg
EUR 508.8

Anti-BDNF Antibody

STJ60050 100 µg
EUR 508.8

Anti-BDNF antibody

STJ73299 100 µg
EUR 430.8

Anti-BDNF antibody

STJ118744 100 µl
EUR 332.4

Anti-BDNF antibody

STJ22789 100 µl
EUR 332.4
Description: This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.

Anti-BDNF (1B10)

YF-MA12115 100 ug
EUR 435.6
Description: Mouse monoclonal to BDNF

Guinea pig Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

DLR-BDNF-Gu-48T 48T
EUR 568.8
Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Brain Derived Neurotrophic Factor (BDNF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Guinea pig Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

DLR-BDNF-Gu-96T 96T
EUR 736.8
Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Brain Derived Neurotrophic Factor (BDNF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Guinea pig Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RDR-BDNF-Gu-48Tests 48 Tests
EUR 591.6

Guinea pig Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RDR-BDNF-Gu-96Tests 96 Tests
EUR 819.6

Guinea pig Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RD-BDNF-Gu-48Tests 48 Tests
EUR 566.4

Guinea pig Brain Derived Neurotrophic Factor (BDNF) ELISA Kit

RD-BDNF-Gu-96Tests 96 Tests
EUR 783.6

BDNF (human)

B5341-.01 10 ug
EUR 711.6

BDNF, Human

HY-P7116A 50ug
EUR 914.4

Anti-pro BDNF antibody

STJ13100047 100 µl
EUR 512.4

Anti-pro BDNF antibody

STJ13100048 500 µg
EUR 512.4

Anti-mature BDNF antibody

STJ13100056 100 µl
EUR 512.4

Anti-mature BDNF antibody

STJ13100057 100 µl
EUR 512.4

Anti-pro BDNF antibody

STJ13100063 100 µl
EUR 512.4

Anti-mature BDNF antibody

STJ13100064 100 µl
EUR 512.4

Rabbit Anti Human Bdnf Polyclonal Antibody

CPBT-65011RH 0.1 mg
EUR 1057.2

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 336

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 336

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 336

BDNF

CH15000 100 ug
EUR 631.2

BDNF

P41014 100 ug Blocking Peptide
EUR 286.8

BDNF

MO15115 500 ug
EUR 1154.4

BDNF

GT41014 100 ug
EUR 546

BDNF

PR15020 5 ug
EUR 428.4

BDNF

PR27080 2 ug
EUR 229.2

BDNF

PR29001 2 ug
EUR 277.2

Human BDNF Antibody

32507-05111 150 ug
EUR 313.2

BDNF, human recombinant

4004-10
EUR 333.6

BDNF, human recombinant

4004-1000
EUR 6571.2

BDNF, human recombinant

4004-250
EUR 2461.2

BDNF, human recombinant

4004-50
EUR 816

Recombinant Human BDNF

P0449 100ug
EUR 626.83
Description: Recombinant Human protein for BDNF

BDNF, human recombinant

P1007-.01 10 µg
EUR 432
Description: Human Brain-Derived Neurotrophic Factor (BDNF) is a member of the NGF family of neurotrophic factors and supports the growth and survivability of nerve and glial cells. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT-3, and NT-4/5

BDNF, human recombinant

P1007-.05 50 µg
EUR 936
Description: Human Brain-Derived Neurotrophic Factor (BDNF) is a member of the NGF family of neurotrophic factors and supports the growth and survivability of nerve and glial cells. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT-3, and NT-4/5

BDNF, human recombinant

P1007-.25 250 µg
EUR 2983.2
Description: Human Brain-Derived Neurotrophic Factor (BDNF) is a member of the NGF family of neurotrophic factors and supports the growth and survivability of nerve and glial cells. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT-3, and NT-4/5

BDNF, human recombinant

P1007-1 1 mg
EUR 7994.4
Description: Human Brain-Derived Neurotrophic Factor (BDNF) is a member of the NGF family of neurotrophic factors and supports the growth and survivability of nerve and glial cells. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT-3, and NT-4/5

Anti-BDNF Rabbit Monoclonal Antibody

M00035-1 100ug/vial
EUR 476.4
Description: Rabbit Monoclonal BDNF Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

BDNF/ Rat BDNF ELISA Kit

ELA-E0011r 96 Tests
EUR 1063.2

Human BDNF shRNA Plasmid

20-abx950425
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Human BDNF ELISA Kit

EHB0036 96Tests
EUR 625.2

Human BDNF ELISA Kit

55R-1556 1 kit
EUR 513.6
Description: ELISA kit for detection of BDNF in the research laboratory

Human BDNF ELISA kit

LF-EK50005 1×96T
EUR 777.6

Human BDNF ELISA Kit

ELA-E0011h 96 Tests
EUR 988.8

BDNF (human) ELISA Kit

K4788-100
EUR 1070.4

BDNF ELISA KIT|Human

EF006120 96 Tests
EUR 826.8

Recombinant Human BDNF Protein

PROTP23560-3 10ug
EUR 380.4
Description: BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues. Recombinant human BDNF is a 27.0 kDa homodimer of two 120 amino acid subunits linked by strong non-covalent interactions. Human and Mouse BDNF sequences are identical.

Antibody for Human BDNF

SPC-703D 0.1mg
EUR 424.8
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is unconjugated.

Antibody for Human BDNF

SPC-703D-A390 0.1mg
EUR 481.2
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to ATTO 390.

Antibody for Human BDNF

SPC-703D-A488 0.1mg
EUR 480
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to ATTO 488.

Antibody for Human BDNF

SPC-703D-A565 0.1mg
EUR 480
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to ATTO 565.

Antibody for Human BDNF

SPC-703D-A594 0.1mg
EUR 480
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to ATTO 594.

Antibody for Human BDNF

SPC-703D-A633 0.1mg
EUR 480
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to ATTO 633.

Antibody for Human BDNF

SPC-703D-A655 0.1mg
EUR 480
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to ATTO 655.

Antibody for Human BDNF

SPC-703D-A680 0.1mg
EUR 480
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to ATTO 680.

Antibody for Human BDNF

SPC-703D-A700 0.1mg
EUR 480
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to ATTO 700.

Antibody for Human BDNF

SPC-703D-ALP 0.1mg
EUR 472.8
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to Alkaline Phosphatase.

Antibody for Human BDNF

SPC-703D-APC 0.1mg
EUR 478.8
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to APC .

Antibody for Human BDNF

SPC-703D-APCCY7 0.1mg
EUR 565.2
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to APC/Cy7.

Antibody for Human BDNF

SPC-703D-BI 0.1mg
EUR 475.2
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to Biotin.

Antibody for Human BDNF

SPC-703D-DY350 0.1mg
EUR 496.8
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to Dylight 350.

Antibody for Human BDNF

SPC-703D-DY405 0.1mg
EUR 483.6
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to Dylight 405.

Antibody for Human BDNF

SPC-703D-DY488 0.1mg
EUR 471.6
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to Dylight 488.

Antibody for Human BDNF

SPC-703D-DY594 0.1mg
EUR 474
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to Dylight 594.

Antibody for Human BDNF

SPC-703D-DY633 0.1mg
EUR 468
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to Dylight 633.

Antibody for Human BDNF

SPC-703D-FITC 0.1mg
EUR 470.4
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to FITC.

Antibody for Human BDNF

SPC-703D-HRP 0.1mg
EUR 465.6
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to HRP.

Antibody for Human BDNF

SPC-703D-P594 0.1mg
EUR 488.4
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to PE/ATTO 594.

Antibody for Human BDNF

SPC-703D-PCP 0.1mg
EUR 478.8
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to PerCP.

Antibody for Human BDNF

SPC-703D-RPE 0.1mg
EUR 476.4
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to RPE .

Antibody for Human BDNF

SPC-703D-STR 0.1mg
EUR 477.6
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is conjugated to Streptavidin.

Antibody for Human BDNF

SPC-703S 0.012mg
EUR 78
Description: A polyclonal antibody for BDNF from Human | Mouse . The antibody is produced in rabbit after immunization with human synthetic peptide from the N-terminal of human BDNF. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This BDNF antibody is unconjugated.

Human BDNF ELISA Kit

STJ150202 1 kit
EUR 494.4
Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of BDNF in human serum, plasma and other biological fluids

Recombinant Human BDNF Protein

RP00308 10 μg
EUR 265.2

Bdnf Antibody

1-CSB-PA16639A0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Bdnf. Recognizes Bdnf from Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:1000-1:5000

BDNF Antibody

1-CSB-PA002655GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against BDNF. Recognizes BDNF from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA

BDNF Antibody

1-CSB-PA002655LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against BDNF. Recognizes BDNF from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

BDNF Antibody

1-CSB-PA05775A0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against BDNF. Recognizes BDNF from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

BDNF Antibody

1-CSB-PA988388
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against BDNF. Recognizes BDNF from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:10000, IHC:1:30-1:150

BDNF Antibody

DF6387 200ul
EUR 420

rHu BDNF

AK8286-0002 2µg Ask for price

rHu BDNF

AK8286-0010 10µg Ask for price

rHu BDNF

AK8286-0100 100µg Ask for price

rHu BDNF

AK8286-1000 1mg Ask for price

BDNF siRNA

20-abx909028
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

BDNF siRNA

20-abx909029
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

BDNF Antibody

1-CSB-PA616184
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against BDNF. Recognizes BDNF from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:10-1:50

BDNF antibody

70R-BR012 50 ug
EUR 327.6
Description: Affinity purified Rabbit polyclonal BDNF antibody

BDNF antibody

70R-6209 50 ug
EUR 560.4
Description: Rabbit polyclonal BDNF antibody raised against the middle region of BDNF

BDNF Antibody

48503-100ul 100ul
EUR 399.6

BDNF Antibody

48503-50ul 50ul
EUR 286.8

BDNF Antibody

48755-100ul 100ul
EUR 399.6

BDNF Antibody

48755-50ul 50ul
EUR 286.8

BDNF Antibody

32263-100ul 100ul
EUR 302.4

BDNF Antibody

5004-100
EUR 392.4

BDNF Peptide

43-146P 0.1 mg
EUR 405.6

BDNF antibody

70R-12244 100 ug
EUR 501.6
Description: Rabbit polyclonal BDNF antibody

BDNF antibody

70R-15327 100 ug
EUR 392.4
Description: Rabbit polyclonal BDNF antibody

BDNF antibody

70R-15985 50 ul
EUR 522
Description: Rabbit polyclonal BDNF antibody

BDNF antibody

70R-13697 100 ug
EUR 418.8
Description: Affinity purified Chicken polyclonal BDNF antibody

BDNF protein

30R-2420 10 ug
EUR 408
Description: Purified recombinant Human BDNF protein

BDNF protein

30R-3318 100 ug
EUR 289.2
Description: Recombinant human BDNF protein

BDNF protein

30R-AB007 2 ug
EUR 159.6
Description: Purified recombinant Human/Mouse/Rat BDNF protein

BDNF antibody

20R-BC001 50 ug
EUR 483.6
Description: Chicken polyclonal BDNF antibody

BDNF antibody

10R-7738 500 ug
EUR 678
Description: Mouse monoclonal BDNF antibody

Downregulation of lengthy noncoding RNA SNHG6 rescued propofol-induced cytotoxicity in human induced pluripotent stem cell-derived cardiomyocytes

 Background: Propofol (PPF) overdose is a uncommon however deadly situation, which can result in extreme cardiac failure. On this research, we established an in vitro PPF-induced cardiac cytotoxicity mannequin, and examine the purposeful function of lengthy non-coding RNA (lncRNA) small nucleolar RNA host gene 6 (SNHG6).

Strategies: Human induced pluripotent stem cell-derived cardiomyocytes (HiPSC-CMs) had been uncovered to PPF in vitro. PPF-induced cytotoxic results had been measured. PPF-induced SNHG6 expression change in HiPSC-CMs had been monitored by qRT-PCR. SNHG6 was downregulated in HiPSC-CMs to look at its function in PPF-induced cardiac cytotoxicity.

The expression of competing endogenous RNA (ceRNA) candidate of SNHG6, human microRNA-186-5p (hsa-miR-186-5p) was additionally investigated in PPF-exposed HiPSC-CMs. Capabilities of hsa-miR-186-5p had been additional investigated in PPF-exposed and SNHG6-downregulated HiPSC-CMs.

Outcomes: PPF induced important cytotoxicity, in addition to SNHG6 upregulation in HiPSC-CMs. SNHG6 downregulation had rescuing results on PPF-induced cardiac cytotoxicity. Twin-luciferase exercise assay confirmed that hsa-miR-186-5p was the ceRNA candidate of SNHG6. QRT-PCR confirmed hsa-miR-186-5p expression was reversely correlated with SNHG6 in PPF-exposed HiPSC-CMs. Suppressing hsa-miR-186-5p lowered the rescuing results of SNHG6-downregulation on PPF-induced cardiac cytotoxicity.

Conclusions: SNHG6/hsa-miR-186-5p can modulate PPF-induced cardiac cytotoxicity in HiPSC-CMs, and thus could also be a future drug goal to forestall PPF infusion syndrome.

Round RNA GLIS2 promotes colorectal most cancers cell motility through activation of the NF-κB pathway 

Round RNAs (circRNAs) are a newly found kind of organic molecule that belongs to the noncoding RNA household. Plentiful proof has proven that circRNAs are concerned within the development of varied cancers. Nevertheless, the actual features of circRNAs in colorectal most cancers (CRC) stay elusive. On this research, we investigated the differentially expressed circRNAs in three pairs of most cancers tissue and adjoining regular tissue of CRC.

We revealed that circGLIS2 expression was greater in CRC tissue and cell traces. Acquire-and-loss perform assays confirmed that circGLIS2 was concerned within the regulation of cell migration. Furthermore, overexpressing circGLIS2 in CRC cells activated the NF-κB pathway and induced pro-inflammatory chemokine manufacturing, which evoked tumor-associated irritation by recruiting leukocytes. In flip, when the most cancers cells had been uncovered to the supernatant of circGLIS2 overexpressed most cancers cells, they had been endowed with the flexibility of migration and chemokines manufacturing.

Moreover, the rescue assay confirmed that circGLIS2 activated NF-κB signaling and promoted cell migration by sponging miR-671. General, our research reveals that circGLIS2, performing as a possible oncogene, maintains the irregular activation state of the NF-κB signaling pathway through the miR-671 sponge mechanism in CRC cells. This research offers a scientific foundation for focusing on circGLIS2 in colorectal most cancers interventions.

The RNA binding protein FMR1 controls selective exosomal miRNA cargo loading throughout irritation 

  • Cells reply to inflammatory illness states by releasing exosomes containing extremely particular protein and RNA cargos, however how irritation alters cargo specificity and secretion of exosomes is unknown.
  • We present that will increase in exosome secretion induced by both viral an infection or LPS/ATP publicity consequence from inflammasome activation and subsequent caspase-1-dependent cleavage of the trafficking adaptor protein RILP.
  • This cleaved type of RILP promotes the motion of multivesicular our bodies towards the cell periphery and induces selective exosomal miRNA cargo loading. We’ve got recognized a standard brief sequence motif current in miRNAs which are selectively loaded into exosomes after RILP cleavage.
  • This motif binds the RNA binding protein FMR1 and directs miRNA loading into exosomes through interplay with elements of the ESCRT (endosomal sorting advanced required for transport) pathway. These outcomes point out that inflammasome-mediated RILP cleavage, and sequence-specific interactions between miRNAs and FMR1, play a big function in exosome cargo loading and enhanced secretion throughout mobile inflammatory responses.

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